Polynucleotides
Polynucleotides represent the cutting edge of regenerative aesthetics—treatments that work with your body's natural healing mechanisms to genuinely repair and rejuvenate skin from within. Unlike treatments that simply fill or relax, polynucleotides stimulate cellular regeneration, offering profound, lasting improvement in skin quality and vitality.
- Stimulates fibroblasts to produce new collagen and elastin
- Powerful antioxidant protection against environmental damage
- Genuine tissue regeneration, not just temporary improvement
- Treats sun damage, scarring, and signs of aging
- Suitable for face, neck, under-eyes and hands
- Long-lasting results that continue improving over months
What Are Polynucleotides?
Polynucleotides are chains of nucleotides—the building blocks of DNA—derived from salmon or trout DNA. When injected into the skin, they act as powerful bio-stimulators, activating fibroblasts to produce new collagen, elastin, and healthy tissue. They also provide antioxidant benefits, protecting cells from damage. This creates genuine regeneration rather than temporary improvement.
How Polynucleotides Regenerate Skin
Polynucleotides work through multiple mechanisms. They stimulate fibroblast activity, increasing collagen and elastin production. Their antioxidant properties neutralise free radicals that cause cellular damage. They improve tissue hydration and promote healing. The combination creates comprehensive skin regeneration—improved texture, firmness, hydration, and overall quality that develops naturally over weeks.
Treatment Protocol
A typical polynucleotide protocol involves 2-4 sessions, spaced 2-4 weeks apart. Treatment takes 30-45 minutes depending on areas treated. We inject the product into specific areas using fine needles or cannulas. You may experience mild swelling or redness for 1-2 days. Results develop gradually as your skin regenerates, with optimal improvement visible 6-8 weeks after completing your course.
Ideal Candidates
Polynucleotides particularly benefit patients with sun-damaged skin, early scarring, fine lines, loss of elasticity, or generally tired-looking skin. They're excellent for the delicate under-eye area where other treatments may not be suitable. Patients seeking genuine regeneration rather than temporary cosmetic improvement find polynucleotides especially rewarding. Results can last 9-12 months or longer.
Frequently Asked Questions
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Polynucleotides work at a cellular level to trigger genuine skin regeneration. Unlike fillers that add volume or Botox® that relaxes muscles, polynucleotides stimulate your own cells to produce new collagen, elastin, and healthy tissue. They also provide antioxidant protection. This creates authentic, lasting improvement in skin quality rather than temporary cosmetic enhancement.
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Yes, polynucleotides have an excellent safety profile. They're derived from purified salmon or trout DNA, which is highly biocompatible with human tissue. The products undergo extensive purification to remove any allergenic proteins. Side effects are typically mild—temporary redness, swelling, or small bumps at injection sites. Serious reactions are extremely rare when administered by qualified practitioners.
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Results typically last 9-12 months, sometimes longer. Because polynucleotides work by stimulating genuine tissue regeneration, the improvements become part of your own skin. Results continue developing for several months after treatment as collagen production increases. Maintenance treatments every 9-12 months help sustain optimal skin quality.
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Yes, polynucleotides are particularly effective for the delicate under-eye area. They can improve dark circles caused by thin skin, reduce fine lines, and improve overall skin quality without the risks associated with fillers in this sensitive area. Many patients who aren't suitable for tear trough fillers achieve excellent results with polynucleotides.
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Both are bio-stimulators, but they work differently. Profhilo uses hyaluronic acid to stimulate collagen and elastin while providing hydration. Polynucleotides use DNA fragments to trigger deeper cellular regeneration and provide antioxidant benefits. Profhilo is excellent for hydration and firmness; polynucleotides excel at genuine tissue repair. They can be combined for comprehensive rejuvenation.
Ready to Start Your Journey?
Book a consultation with Dr. Annette Phillips to discuss your goals and discover if Polynucleotides is right for you.
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